Intramolecular structure and dynamics in computationally designed peptide-based polymers displaying tunable chain stiffness
Sinha, Nairiti J.
Kloxin, Christopher J.
Saven, Jeffery G.
Jensen, Grethe V.
Pochan, Darrin J
Physical Review Materials
Polymers assembled using computationally designed coiled coil bundlemers display tunable stiffness via control of interbundlemer covalent connectivity as confirmed using small-angle neutron scattering. Neutron spin echo spectroscopy reveals that rigid rod polymers show a decay rate Γ∼Q2 (Q is the scattering vector) expected of straight cylinders. Semirigid polymers assembled using bundlemers linked via 4-armed organic linker show flexible segmental dynamics at mid-Q and Γ∼Q2 behavior at high Q. The results give insight into linker flexibility-dependent interbundlemer dynamics in the hybrid polymers.
This article was originally published in Physical Review Materials. The version of record is available at: https://doi.org/10.1103/PhysRevMaterials.5.095601
Sinha, Nairiti J., Yi Shi, Yao Tang, Christopher J. Kloxin, Jeffery G. Saven, Antonio Faraone, Grethe V. Jensen, and Darrin J. Pochan. 2021. “Intramolecular Structure and Dynamics in Computationally Designed Peptide-Based Polymers Displaying Tunable Chain Stiffness.” Phys. Rev. Materials 5 (9): 095601. https://doi.org/10.1103/PhysRevMaterials.5.095601.