• Predicting, controlling and molecular understanding of therapeutic protein self-interactions: a combined experimental and computational approach 

  Shahfar, Hassan (University of Delaware, 2022)

  Protein self-interactions (PSI) influence biophysical properties like aggregation, solubility, viscosity, and phase separation of drug products. PSI are a function of protein identity (e.g., sequence, charge, and hydrophobicity ...
• Live load distribution and evaluation of bridges using digital image measurements 

  Timber, Luke C. (University of Delaware, 2022)

  In this study, non-contact, vision-based measurement techniques using digital image correlation are compared to displacement measurements obtained from mounted sensors to analyze the live load distribution in two ...
• Electronic properties of topological semimetals, and wide-gap oxide semiconductors using hybrid density functional theory 

  Khalid, Shoaib (University of Delaware, 2022)

  Computational materials science is at the forefront of discovering new materials and predicting novel material properties with much improved efficiency. In this work we used first principles methods based on density ...
• Synthetic efforts toward the total synthesis of psiguadial A & HPLC method development for artemisinin metabolites 

  Achtenhagen, Marcel (University of Delaware, 2022)

  Chapter 1 outlines the diverse collection of natural products that are classified as meroterpenoid natural products. Taking a closer look at their biological background as well as the plant systems that produce these ...
• Test fraud: practical applications and operational considerations for the detection of item preknowledge and compromised content with real data 

  Ross, Linette P. (University of Delaware, 2022)

  One of the most serious forms of cheating occurs when examinees have item preknowledge and prior access to secure test material before taking an exam for the purpose of obtaining an inflated test score. Examinees that cheat ...
• An engineered hydrogel platform for understanding breast cancer dormancy, reactivation, and chemoresistance for drug development 

  Farino Reyes, Cindy J. (University of Delaware, 2022)

  Metastasis remains the leading cause of cancer-associated death worldwide. A latency period ranging from months to decades is often observed prior to relapse as disseminated tumor cells (DTCs) can undergo dormancy upon ...
• A potential mechanism sustaining the biological hotspot around Palmer Deep Canyon 

  Hudson, Katherine L. (University of Delaware, 2022)

  Palmer Deep Canyon (PDC) is a submarine canyon located along the Western Antarctic Peninsula. The region is considered a biological hotspot due to the high number of marine predators during the austral summer. The mechanisms ...
• Analysis of relationship between track geometry defects and measured track subsurface condition using different machine learning methods 

  Nguyen, Mike (University of Delaware, 2022)

  This research aims to enhance the further study of the relationship between track geometry defects and measured track substructure condition and to provide a mechanism to allow railroads to take proper preventive maintenance ...
• Whanau (families) in sport: parent volunteering and young peoples physical literacy development 

  Andrews, Lara (University of Delaware, 2022)

  Using the Family Systems lens and the physical literacy approach, this dissertation examined the association of parent volunteering in sport and young people’s physical literacy development. The Active NZ surveys were ...
• Understanding the effects of wearing a quantitatively prescribed passive-dynamic ankle-foot orthosis on the mechanical cost-of-transport and gait velocity in individuals post-stroke 

  Koller, Corey A. (University of Delaware, 2022)

  Individuals post-stroke are commonly prescribed passive-dynamic ankle-foot orthoses (PD-AFOs) to aid in the control of shank forward rotation during mid-to- terminal stance due to plantar flexor weakness. PD-AFO bending ...
• Adaptive real-time coaching in free-living conditions 

  Saponaro, Matthew (University of Delaware, 2022)

  Physical inactivity and prolonged sedentary behavior is strongly linked to cardiovascular disease. Strikingly, almost 90 percent of US adults report being inactive with majority of waking hours spent sedentary. Sedentary ...
• Secure and privacy-preserving data aggregation in wireless sensor networks 

  Aseeri, Aishah (University of Delaware, 2022)

  Wireless sensor networks (WSNs) are widely expected to play an important role in future IoT-power smart cities, which are expected to have all kinds of embedded sensors continuously sensing the city space and generating ...
• A neural network-based ultra-high energy neutrino reconstruction method with the Askaryan Radio Array 

  Pan, Yue (University of Delaware, 2022)

  Ultra-high energy (UHE) neutrinos ($E_{\nu} > 10^{17}$~eV) are important messenger particles that can carry information about the most intense processes in the Universe, far beyond any experiment that human beings can do ...
• Assessing service and support disparities among families of children on the autism spectrum 

  Sticinski, Ethel Virginia (University of Delaware, 2022)

  Families with children on the autism spectrum have critical service and support needs which intensify as their children reach adulthood. Use of autism-related services and social support are related to positive outcomes ...
• The cumulative effects of prolonged repetitive head impact exposure into adulthood 

  Hunzinger, Katherine J. (University of Delaware, 2022)

  BACKGROUND: Roughly 70-90% of the 2.8 million traumatic brain injuries (TBIs) that occur annually are mild (mTBI). Although a fairly benign injury, acutely, with clinical sign and symptom resolution occurring devoid of ...
• The effects of horizontal fiscal equalization on the expenditures of local governments: the case of Seoul, Korea 

  Kim, Minhee (University of Delaware, 2022)

  The role of Fiscal Equalization (FE) transfers in economic development has been discussed extensively in studies of local/regional public finance. In a fiscally decentralized system, FE aims not just at reducing fiscal ...
• Impact damage evolution of plain weave composites: multiscale modeling and experiments 

  Meyer, Christopher Scott (University of Delaware, 2022)

  Recent developments in plain weave glass/epoxy composites have led to their increasing dual use as a structural and protective material in light armored vehicles. As such, understanding the evolution of damage due to ...
• Machine-learning-enabled multiscale modeling for catalysis and engineering: from data, algorithms to software applications 

  Wang, Yifan (University of Delaware, 2022)

  Catalytic processes produce most of the chemicals today and will continue to provide energy and materials for future generations. Advances in catalyst discovery and efficient industrial processes could mitigate climate ...
• Multi-sensor deep learning for autonomous population monitoring of marine species 

  Zhao, Jiayi (University of Delaware, 2022)

  Monitoring marine species, both at an individual and population level, is a critical part of protecting the marine ecosystem and managing modern fisheries. The development and utilization of Autonomous Underwater Vehicles ...
• Marker expression in glioblastoma stem cells grown in vitro and after transplanation into a chick embryo xenograft brain tumor model 

  Doerr, Jackson (University of Delaware, 2022)

  Glioblastoma (GBM) is the most aggressive form of brain cancer that arises in situ from transformed neural stem cells, progenitor cells, or differentiated astrocytes. It is classified as World Health Organization (WHO) ...

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