Acid-Base Metabolism And The Protein Condition

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Rand Corporation

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This Memorandum applies the proton condition of inorganic chemistry to the problem of describing the net acid content in a biological system. A "proton content" is defined which expresses the net acid content in terms of the detailed chemical composition of the system. This approach is compared with previous approaches to the quantitative description of acid-base metabolism and then applied to the interpretation of experimental metabolic balances.

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