Clinical Applications of Body Composition and Functional Status Tools for Nutritional Assessment of Hospitalized Adults: A Systematic Review

Abstract
Introduction: No global consensus exists on diagnostic criteria for malnutrition. Muscular deficits and functional impairments are major components of available malnutrition diagnostic frameworks (SGA, MCC, EDC, GLIM), because these facets of nutritional status significantly impact outcomes. The purpose of this review is to explore which body composition (BCA) and functional status assessment (FSA) tools are being used for nutritional assessment (NA) and monitoring response to nutritional interventions (RNI) in adult inpatients. Methods: A literature search of Embase, Medline (Ovid), Web of Science and Cochrane Central was performed to identify studies that utilized BCA and/or FSA tools for NA (along with an accepted NA diagnostic framework) and/or for monitoring RNI in adult inpatients. Results: The search yielded 3,667 articles; 94 were included in the review. The number of studies using BCA and/or FSA tools for NA was 47, and for monitoring RNI was also 47. 79% of studies used bioimpedance for BCA and 97% that included FSA utilized hand-grip strength. When compared against sets of diagnostic criteria, many of the BCA and FSA tools showed promising associations with nutritional status. Conclusions: Bioimpedance methods are the most widely used bedside BCA tools, and HGS is the most widely used FSA tool; however, these methods are being used with a variety of protocols, algorithms, and interpretation practices in heterogeneous populations. In order to create a standardized NSA process there is a need for validation studies on bedside methods and development of globally standardized assessment protocols in clinical inpatient settings.
Description
This is the peer reviewed version of the following article: Smith, LO, Olieman, JF, Berk, KA, Ligthart-Melis, GC, Earthman, CP. Clinical applications of body composition and functional status tools for nutrition assessment of hospitalized adults: a systematic review. J Parenter Enteral Nutr. 2022; 1- 19. doi:10.1002/jpen.2444, which has been published in final form at https://doi.org/10.1002/jpen.2444. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited. This article will be embargoed until 12/09/2023.
Keywords
body composition, fat-free mass, functional status, hospital, inpatient, lean tissue, Malnutrition, muscle, nutrition support practice, nutritional assessment
Citation
Smith, LO, Olieman, JF, Berk, KA, Ligthart-Melis, GC, Earthman, CP. Clinical applications of body composition and functional status tools for nutrition assessment of hospitalized adults: a systematic review. J Parenter Enteral Nutr. 2022; 1- 19. doi:10.1002/jpen.2444