Browsing by Author "Tognolli,Michael"
Now showing 1 - 1 of 1
Results Per Page
Sort Options
Item The UniProtKB guide to the human proteome(Oxford University Press, 2/19/16) Breuza,Lionel; Poux,Sylvain; Estreicher,Anne; Famiglietti,Maria Livia; Magrane,Michele; Tognolli,Michael; Bridge,Alan; Baratin,Delphine; Redaschi,Nicole; UniProt Consortium; Lionel Breuza, Sylvain Poux, Anne Estreicher, Maria Livia Famiglietti, Michele Magrane, Michael Tognolli, Alan Bridge, Delphine Baratin, Nicole Redaschi and The UniProt Consortium; Wu, Cathy Huey-HwaAdvances in high-throughput and advanced technologies allow researchers to routinely perform whole genome and proteome analysis. For this purpose, they need high-quality resources providing comprehensive gene and protein sets for their organisms of interest. Using the example of the human proteome, we will describe the content of a complete proteome in the UniProt Knowledgebase (UniProtKB). We will show how manual expert curation of UniProtKB/Swiss-Prot is complemented by expert-driven automatic annotation to build a comprehensive, high-quality and traceable resource. We will also illustrate how the complexity of the human proteome is captured and structured in UniProtKB.