COVID-19 Knowledge Graph from semantic integration of biomedical literature and databases

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dc.contributor.authorChen, Chuming
dc.contributor.authorRoss, Karen E.
dc.contributor.authorGavali, Sachin
dc.contributor.authorCowart, Julie E.
dc.contributor.authorWu, Cathy H.
dc.date.accessioned2022-01-31T15:49:41Z
dc.date.available2022-01-31T15:49:41Z
dc.date.issued2021-10-06
dc.descriptionThis is a pre-copyedited, author-produced version of an article accepted for publication in Bioinformatics following peer review. The version of record Chuming Chen, Karen E Ross, Sachin Gavali, Julie E Cowart, Cathy H Wu, COVID-19 Knowledge Graph from semantic integration of biomedical literature and databases, Bioinformatics, Volume 37, Issue 23, 1 December 2021, Pages 4597–4598, https://doi.org/10.1093/bioinformatics/btab694 is available online at: https://doi.org/10.1093/bioinformatics/btab694.en_US
dc.description.abstractThe global response to the COVID-19 pandemic has led to a rapid increase of scientific literature on this deadly disease. Extracting knowledge from biomedical literature and integrating it with relevant information from curated biological databases is essential to gain insight into COVID-19 etiology, diagnosis and treatment. We used Semantic Web technology RDF to integrate COVID-19 knowledge mined from literature by iTextMine, PubTator and SemRep with relevant biological databases and formalized the knowledge in a standardized and computable COVID-19 Knowledge Graph (KG). We published the COVID-19 KG via a SPARQL endpoint to support federated queries on the Semantic Web and developed a knowledge portal with browsing and searching interfaces. We also developed a RESTful API to support programmatic access and provided RDF dumps for download.en_US
dc.description.sponsorshipThis work was partially supported by the National Institutes of Health [U24HG007822 and R35GM141873] and institutional resources at the University of Delaware.en_US
dc.identifier.citationChuming Chen, Karen E Ross, Sachin Gavali, Julie E Cowart, Cathy H Wu, COVID-19 Knowledge Graph from semantic integration of biomedical literature and databases, Bioinformatics, Volume 37, Issue 23, 1 December 2021, Pages 4597–4598, https://doi.org/10.1093/bioinformatics/btab694en_US
dc.identifier.issn1460-2059
dc.identifier.urihttps://udspace.udel.edu/handle/19716/30218
dc.language.isoen_USen_US
dc.publisherBioinformaticsen_US
dc.titleCOVID-19 Knowledge Graph from semantic integration of biomedical literature and databasesen_US
dc.typeArticleen_US

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