Racial and Ethnic Heterogeneity in the Association Between Total Cholesterol and Pediatric Obesity
| Author(s) | Holmes, Laurens Jr. | |
| Author(s) | LaHurd, Alex | |
| Author(s) | Wasson, Emily | |
| Author(s) | McClarin, Lavisha | |
| Author(s) | Dabney, Kirk | |
| Ordered Author | Laurens Holmes Jr., Alex LaHurd, Emily Wasson, Lavisha McClarin and Kirk Dabney | |
| UD Author | LaHurd, Alex | en_US |
| UD Author | Holmes, Laurens Jr. | en_US |
| Date Accessioned | 2016-10-13T13:54:19Z | |
| Date Available | 2016-10-13T13:54:19Z | |
| Copyright Date | Copyright © 2015 by the authors; licensee MDPI, Basel, Switzerland. | en_US |
| Publication Date | 2015-12-23 | |
| Description | Publisher's PDF | en_US |
| Abstract | Total cholesterol (TC) directly correlates with overweight/obesity, but it remains unclear if this association varies by race and ethnicity. We assessed the association as well as the racial/ethnic heterogeneity in this relationship. Data on 63,863 children were assessed using electronic medical records between 2010 and 2011. A cross-sectional design was utilized with log-binomial regression model and chi-squared statistic to examine the data. Overall, abnormal total cholesterol (ATC) was 7.5% (4812). Significant racial variability in ATC was observed: Black/African American (AA) (7.4%), White (7.0%), Asian (5.1%) and some other race (SOR) children (11.3%), 2 (5) = 141.5, p < 0.0001. Black/AA (34.7%) and SOR children (41.2%) were predominantly overweight/obese, unlike the Asian children, (25.8%), 2 (5) = 324.6, p < 0.0001. The BMI percentile was highest among SOR (69.0 28.6) and Black/AA children (65.2 29.1), but lowest among Asian children (55.7 31.5). A significant racial variability was also observed in weight, with the highest mean among Black/AA children (36.8kg 23.0) and the lowest among Asian children (28.7kg 16.8), f = 7.2, p < 0.001. Relative to normal TC, children with ATC were 2.6 times as likely to have abnormal BMI, relative risk (RR) =2.60, 99% CI, 2.54–2.68). Compared to non-Hispanic (RR = 2.62, 99% CI, 2.54–2.69), the risk was lower among Hispanics (RR = 2.34, 99%, 2.21–2.48). Among children with ATC, risk for abnormal BMI was highest among Asians, adjusted RR = 2.91, 99% CI, 2.34–3.62), intermediate among AA (ARR = 2.68, 99% CI, 2.59–2.77), but lowest among Whites (ARR = 2.40, 99% CI, 2.39–2.64), and SOR (ARR = 2.33, 99% CI, 2.19–2.50). In a large sample of children, total cholesterol directly correlates with BMI, with an observed racial and ethnic heterogeneity. | en_US |
| Department | University of Delaware. Department of Biological Sciences. | en_US |
| Citation | Holmes, Laurens, et al. "Racial and Ethnic Heterogeneity in the Association Between Total Cholesterol and Pediatric Obesity." International journal of environmental research and public health 13.1 (2015): 19. | en_US |
| DOI | doi:10.3390/ijerph13010019 | en_US |
| ISSN | 1661-7827 ; e- 1660-4601 | en_US |
| URL | http://udspace.udel.edu/handle/19716/19807 | |
| Language | en_US | en_US |
| Publisher | MDPI | en_US |
| dc.rights | CC-BY 4.0, https://creativecommons.org/licenses/by/4.0/ | en_US |
| dc.source | International Journal of Environmental Research and Public Health | en_US |
| dc.source.uri | http://www.mdpi.com/journal/ijerph | en_US |
| Title | Racial and Ethnic Heterogeneity in the Association Between Total Cholesterol and Pediatric Obesity | en_US |
| Type | Article | en_US |
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