Advances in Poultry Vaccines: Leveraging Biotechnology for Improving Vaccine Development, Stability, and Delivery

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Author(s)Abdelaziz, Khaled
Author(s)Helmy, Yosra A.
Author(s)Yitbarek, Alexander
Author(s)Hodgins, Douglas C.
Author(s)Sharafeldin, Tamer A.
Author(s)Selim, Mohamed S. H.
Date Accessioned2024-04-05T19:19:49Z
Date Available2024-04-05T19:19:49Z
Publication Date2024-01-29
DescriptionThis article was originally published in Vaccines. The version of record is available at: https://doi.org/10.3390/vaccines12020134. © 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
AbstractWith the rapidly increasing demand for poultry products and the current challenges facing the poultry industry, the application of biotechnology to enhance poultry production has gained growing significance. Biotechnology encompasses all forms of technology that can be harnessed to improve poultry health and production efficiency. Notably, biotechnology-based approaches have fueled rapid advances in biological research, including (a) genetic manipulation in poultry breeding to improve the growth and egg production traits and disease resistance, (b) rapid identification of infectious agents using DNA-based approaches, (c) inclusion of natural and synthetic feed additives to poultry diets to enhance their nutritional value and maximize feed utilization by birds, and (d) production of biological products such as vaccines and various types of immunostimulants to increase the defensive activity of the immune system against pathogenic infection. Indeed, managing both existing and newly emerging infectious diseases presents a challenge for poultry production. However, recent strides in vaccine technology are demonstrating significant promise for disease prevention and control. This review focuses on the evolving applications of biotechnology aimed at enhancing vaccine immunogenicity, efficacy, stability, and delivery.
SponsorThis work is supported by the USDA National Institute of Food and Agriculture, Hatch Project number SC-1700628 (Accession Number 7004405 and Technical Contribution No. 7259).
CitationAbdelaziz K, Helmy YA, Yitbarek A, Hodgins DC, Sharafeldin TA, Selim MSH. Advances in Poultry Vaccines: Leveraging Biotechnology for Improving Vaccine Development, Stability, and Delivery. Vaccines. 2024; 12(2):134. https://doi.org/10.3390/vaccines12020134
ISSN2076-393X
URLhttps://udspace.udel.edu/handle/19716/34249
Languageen_US
PublisherVaccines
dc.rightsAttribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
Keywordspoultry
Keywordschicken
Keywordsbiotechnology
Keywordsvaccine
Keywordsinactivated
Keywordsattenuated
KeywordsDNA
KeywordsmRNA
Keywordssubunit
Keywordsrecombinant
Keywordsadjuvant
Keywordsstability
Keywordsdelivery
Keywordsin ovo
Keywordsnanoparticles
TitleAdvances in Poultry Vaccines: Leveraging Biotechnology for Improving Vaccine Development, Stability, and Delivery
TypeArticle
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