Catch and release: photocleavable cationic diblock copolymers as a potential platform for nucleic acid delivery

Simple item page
dc.contributor.authorGreen, Matthew D.
dc.contributor.authorFoster, Abbygail A.
dc.contributor.authorGreco, Chad T.
dc.contributor.authorRoy, Raghunath
dc.contributor.authorLehr, Rachel M.
dc.contributor.authorEpps, Thomas H. III
dc.contributor.authorSullivan, Millicent O.
dc.contributor.orderedauthorMatthew D. Green, Abbygail A. Foster, Chad T. Greco, Raghunath Roy, Rachel M. Lehr, Thomas H. Epps, III and Millicent O. Sullivan
dc.contributor.udauthorGreen, Matthew D.en_US
dc.contributor.udauthorFoster, Abbygail A.en_US
dc.contributor.udauthorGreco, Chad T.en_US
dc.contributor.udauthorRoy, Raghunathen_US
dc.contributor.udauthorLehr, Rachel M.en_US
dc.contributor.udauthorEpps, Thomas H. IIIen_US
dc.contributor.udauthorSullivan, Millicent O.en_US
dc.date.accessioned2016-03-16T15:33:43Z
dc.date.available2016-03-16T15:33:43Z
dc.date.copyrightCopyright © The Royal Society of Chemistry 2014.en_US
dc.date.issued2014-06-05
dc.descriptionPublisher's PDFen_US
dc.description.abstractBinding interactions between DNA and cationic nanocarriers must be sufficiently strong to prevent nuclease-mediated degradation, yet weak enough to permit transcription. We demonstrate cationic diblock copolymers containing PEG and o-nitrobenzyl moieties that facilitated tailorable DNA complexation and light-activated release. This design unlocks a new approach to improved non-viral gene packaging.en_US
dc.description.departmentUniversity of Delaware. Department of Chemical & Biomolecular Engineering.en_US
dc.identifier.citationThomas III, H. "Catch and release: photocleavable cationic diblock copolymers as a potential platform for nucleic acid delivery." Polymer chemistry 5.19 (2014): 5535-5541.en_US
dc.identifier.doiDOI: 10.1039/C4PY00638Ken_US
dc.identifier.issn1759-9954 ; e- 1759-9962en_US
dc.identifier.urihttp://udspace.udel.edu/handle/19716/17509
dc.language.isoen_USen_US
dc.publisherRoyal Society of Chemistryen_US
dc.rightsArticle is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.en_US
dc.sourcePolymer Chemistryen_US
dc.source.urihttp://www.rsc.org/journals-books-databases/about-journals/polymer-chemistry/en_US
dc.titleCatch and release: photocleavable cationic diblock copolymers as a potential platform for nucleic acid deliveryen_US
dc.typeArticleen_US

Files

Original bundle

Now showing 1 - 2 of 2
Thumbnail Image
Name:
RSC Catch and release suppl_1448463533T4633.pdf
Size:
8.29 MB
Format:
Adobe Portable Document Format
Description:
Download
Thumbnail Image
Name:
c4py00638k1.pdf
Size:
1.12 MB
Format:
Adobe Portable Document Format
Description:
Supplemental material
Download

License bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
2.22 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Open Access Publications - Department of Chemical and Biomolecular Engineering