Fatness QTL on chicken chromosome 5 and interaction with sex
Date
2006
Journal Title
Journal ISSN
Volume Title
Publisher
EDP Sciences
Abstract
Quantitative trait loci (QTL) affecting fatness in male chickens were previously
identified on chromosome 5 (GGA5) in a three-generation design derived from two experimental
chicken lines divergently selected for abdominal fat weight. A new design, established from
the same pure lines, produced 407 F2 progenies (males and females) from 4 F1-sire families.
Body weight and abdominal fat were measured on the F2 at 9 wk of age. In each sire family,
selective genotyping was carried out for 48 extreme individuals for abdominal fat using seven
microsatellite markers from GGA5. QTL analyses confirmed the presence of QTL for fatness
on GGA5 and identified a QTL by sex interaction. By crossing one F1 sire heterozygous at
the QTL with lean line dams, three recombinant backcross 1 (BC1) males were produced and
their QTL genotypes were assessed in backcross 2 (BC2) progenies. These results confirmed
the QTL by sex interaction identified in the F2 generation and they allow mapping of the female
QTL to less than 8 Mb at the distal part of the GGA5. They also indicate that fat QTL alleles
were segregating in both fat and lean lines.
Description
Final published version
Keywords
QTL × sex interaction, Meat-type chickens, Quantitative trait loci, Fatness QT
Citation
Abasht, B., Pitel, F., Lagarrigue, S., Le Bihan-Duval, E., Le Roy, P., Demeure, O., . . . Douaire, M. (2006). Fatness QTL on chicken chromosome 5 and interaction with sex. Genetics Selection Evolution, 38(3), 297-311. doi:10.1051/gse:2006005