Mathematical Analysis And Digital Simulation Of The Respiratory Control System

Author(s)Grodins, Fred S. M.D.
Author(s)Buell, June
Author(s)Bart, Alex J.
Date Accessioned2005-07-22T18:20:55Z
Date Available2005-07-22T18:20:55Z
Publication Date1967-03
AbstractThis Memorandum expresses the basic material balance relationships for the lung-blood-tissue gas transport and exchange system in a set of differential-difference equations containing a number of dependent time delays. Additional equations define the chemical details of transport and acid-base buffering, concentration equilibria, and blood flow behavior. Finally, a control function is included defining the dependence of ventilation upon CSF (H ), and PO2 at the carotid chemoceptors. A Fortran program was written for convenient digital simulation of the responses of the system to a wide variety of forcings, including C02 inhalation, hypoxia at: sea level, altitude hypoxia, and metabolic disturbances in acid-base balance. Both dynamic and steady-state behavior of the model were reasonably realistic.en
SponsorU.S. Air Forceen
Extent1923371 bytes
MIME typeapplication/pdf
URLhttp://udspace.udel.edu/handle/19716/1401
Languageen_US
PublisherRand Corporationen
Part of SeriesCⅇ40
KeywordsMathematical Analysisen
KeywordsDigital Simulationen
KeywordsRespiratory Controlen
TitleMathematical Analysis And Digital Simulation Of The Respiratory Control Systemen
TypeTechnical Reporten
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