Mathematical Analysis And Digital Simulation Of The Respiratory Control System
Author(s) | Grodins, Fred S. M.D. | |
Author(s) | Buell, June | |
Author(s) | Bart, Alex J. | |
Date Accessioned | 2005-07-22T18:20:55Z | |
Date Available | 2005-07-22T18:20:55Z | |
Publication Date | 1967-03 | |
Abstract | This Memorandum expresses the basic material balance relationships for the lung-blood-tissue gas transport and exchange system in a set of differential-difference equations containing a number of dependent time delays. Additional equations define the chemical details of transport and acid-base buffering, concentration equilibria, and blood flow behavior. Finally, a control function is included defining the dependence of ventilation upon CSF (H ), and PO2 at the carotid chemoceptors. A Fortran program was written for convenient digital simulation of the responses of the system to a wide variety of forcings, including C02 inhalation, hypoxia at: sea level, altitude hypoxia, and metabolic disturbances in acid-base balance. Both dynamic and steady-state behavior of the model were reasonably realistic. | en |
Sponsor | U.S. Air Force | en |
Extent | 1923371 bytes | |
MIME type | application/pdf | |
URL | http://udspace.udel.edu/handle/19716/1401 | |
Language | en_US | |
Publisher | Rand Corporation | en |
Part of Series | Cⅇ40 | |
Keywords | Mathematical Analysis | en |
Keywords | Digital Simulation | en |
Keywords | Respiratory Control | en |
Title | Mathematical Analysis And Digital Simulation Of The Respiratory Control System | en |
Type | Technical Report | en |