Nitsche, Joseph2015-10-082015-10-082015-05http://udspace.udel.edu/handle/19716/17096High Performance Liquid Chromatography (HPLC) is a very important separation technique. This study attempted to create nonspherical iron oxide-based colloidal particles to be used as the cores in core-shell particles used as the support material for the stationary phase used in HPLC. The cores were coated with an impenetrable layer of silica to protect the cores from breaking down and to keep solutes away from iron. A porous layer was then added to the cores using a silica sol that were held together by a polymer. All of the colloids synthesized in this study were characterized using SEM and FIB-SEM. This study also included the creation of a Continuous Flow Steric Field-Flow Fractionator to be used to separate colloidal particles based on size, density, and shape.en-USResearch Subject Categories::TECHNOLOGY::Chemical engineeringResearch Subject Categories::TECHNOLOGY::Chemical engineering::Chemical process and manufacturing engineeringChemical EngineeringThesis