Neural Dynamics during Binocular Rivalry: Indications from Human Lateral Geniculate Nucleus

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Author(s)Yildirim, Irem
Author(s)Schneider, Keith A.
Date Accessioned2023-03-16T15:24:12Z
Date Available2023-03-16T15:24:12Z
Publication Date2023-01-06
DescriptionThis article was originally published in eNeuro. The version of record is available at: https://doi.org/10.1523/ENEURO.0470-22.2022
AbstractWhen two sufficiently different stimuli are presented to each eye, perception alternates between them. This binocular rivalry is conceived as a competition for representation in the single stream of visual consciousness. The magnocellular (M) and parvocellular (P) pathways, originating in the retina, encode disparate information, but their potentially different contributions to binocular rivalry have not been determined. Here, we used functional magnetic resonance imaging to measure the human lateral geniculate nucleus (LGN), where the M and P neurons are segregated into layers receiving input from a single eye. We had three participants (one male, two females) and used achromatic stimuli to avoid contributions from color opponent neurons that may have confounded previous studies. We observed activity in the eye-specific regions of LGN correlated with perception, with similar magnitudes during rivalry or physical stimuli alternations, also similar in the M and P regions. These results suggest that LGN activity reflects our perceptions during binocular rivalry and is not simply an artifact of color opponency. Further, perception appears to be a global phenomenon in the LGN, not just limited to a single information channel. Significance Statement Multiple channels of visual information emerge from the retina, but their role in our visual perception remains unclear. Binocular rivalry is an interesting phenomenon in that the separate stimuli presented to each eye remain stable, yet our conscious perception alternates between them. We tested whether both the magnocellular and parvocellular visual streams contribute to binocular rivalry. We measured their activations during binocular rivalry in the human lateral geniculate nucleus, where these two streams are physically disjoint. We found that unperceived information in both streams was suppressed during binocular rivalry, suggesting that both the magnocellular and parvocellular streams have a role in our conscious perception.
SponsorThis work was supported by National Institutes of Health | National Eye Institute Grant 1R01-EY-028266 (to K.A.S.).
CitationYildirim, Irem, and Keith A. Schneider. “Neural Dynamics during Binocular Rivalry: Indications from Human Lateral Geniculate Nucleus.” Eneuro 10, no. 1 (2023): ENEURO.0470-22.2022. https://doi.org/10.1523/ENEURO.0470-22.2022.
ISSN2373-2822
URLhttps://udspace.udel.edu/handle/19716/32461
Languageen_US
PublishereNeuro
Keywordsbinocular rivalry
KeywordsfMRI
Keywordslateral geniculate nucleus
Keywordsmagnocellular
Keywordsparvocellular
TitleNeural Dynamics during Binocular Rivalry: Indications from Human Lateral Geniculate Nucleus
TypeArticle
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