Stuttering: Our Current Knowledge, Research Opportunities, and Ways to Address Critical Gaps

dc.contributor.authorChang, Soo-Eun
dc.contributor.authorBelow, Jennifer E.
dc.contributor.authorChow, Ho Ming
dc.contributor.authorGuenther, Frank H.
dc.contributor.authorHampton Wray, Amanda M.
dc.contributor.authorJackson, Eric S.
dc.contributor.authorMax, Ludo
dc.contributor.authorNeef, Nicole E.
dc.contributor.authorSheikhBahaei, Shahriar
dc.contributor.authorShekim, Lana
dc.contributor.authorTichenor, Seth E.
dc.contributor.authorWalsh, Bridget
dc.contributor.authorWatkins, Kate E.
dc.contributor.authorYaruss, J. Scott
dc.contributor.authorBernstein Ratner, Nan
dc.date.accessioned2025-04-23T20:15:20Z
dc.date.available2025-04-23T20:15:20Z
dc.date.issued2025-04-02
dc.descriptionThis article was originally published in Neurobiology of Language. The version of record is available at: https://doi.org/10.1162/nol_a_00162. © 2025 Massachusetts Institute of Technology. Published under a Creative Commons Attribution 4.0 International (CC BY 4.0) license. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. For a full description of the license, please visit https://creativecommons.org/licenses/by/4.0/legalcode.
dc.description.abstractOur understanding of the neurobiological bases of stuttering remains limited, hampering development of effective treatments that are informed by basic science. Stuttering affects more than 5% of all preschool-age children and remains chronic in approximately 1% of adults worldwide. As a condition that affects a most fundamental human ability to engage in fluid and spontaneous verbal communication, stuttering can have substantial psychosocial, occupational, and educational impacts on those who are affected. This article summarizes invited talks and breakout sessions that were held in June 2023 as part of a 2-day workshop sponsored by the US National Institute on Deafness and Other Communication Disorders. The workshop encompassed topics including neurobiology, genetics, speech motor control, cognitive, social, and emotional impacts, and intervention. Updates on current research in these areas were summarized by each speaker, and critical gaps and priorities for future research were raised, and then discussed by participants. Research talks were followed by smaller, moderated breakout sessions intended to elicit diverse perspectives, including on the matter of defining therapeutic targets for stuttering. A major concern that emerged following participant discussion was whether priorities for treatment in older children and adults should focus on targeting core speech symptoms of stuttering, or on embracing effective communication regardless of whether the speaker exhibits overt stuttering. This article concludes with accumulated convergent points endorsed by most attendees on research and clinical priorities that may lead to breakthroughs with substantial potential to contribute to bettering the lives of those living with this complex speech disorder.
dc.description.sponsorshipJennifer Below, National Institute on Deafness and Other Communication Disorders (https://dx.doi.org/10.13039/100000055), Award ID: R01DC017175. Jennifer Below, National Institute on Deafness and Other Communication Disorders (https://dx.doi.org/10.13039/100000055), Award ID: R03DC015329. Soo-Eun Chang, National Institute on Deafness and Other Communication Disorders (https://dx.doi.org/10.13039/100000055), Award ID: R01DC011277. Soo-Eun Chang, National Institute on Deafness and Other Communication Disorders (https://dx.doi.org/10.13039/100000055), Award ID: R01DC018283. Ho Ming Chow, National Institute on Deafness and Other Communication Disorders (https://dx.doi.org/10.13039/100000055), Award ID: R21DC015853. Frank Guenther, National Institute on Deafness and Other Communication Disorders (https://dx.doi.org/10.13039/100000055), Award ID: R01DC007683. Nan Bernstein Ratner, National Institute on Deafness and Other Communication Disorders (https://dx.doi.org/10.13039/100000055), Award ID: R01DC015494. Nan Bernstein Ratner, National Institute on Deafness and Other Communication Disorders (https://dx.doi.org/10.13039/100000055), Award ID: R01DC307764. Bridget Walsh, National Institute on Deafness and Other Communication Disorders (https://dx.doi.org/10.13039/100000055), Award ID: R03DC013402. Bridget Walsh, National Institute on Deafness and Other Communication Disorders (https://dx.doi.org/10.13039/100000055), Award ID: R01DC018000. Ludo Max, National Institute on Deafness and Other Communication Disorders (https://dx.doi.org/10.13039/100000055), Award ID: R01DC017444. Ludo Max, National Institute on Deafness and Other Communication Disorders (https://dx.doi.org/10.13039/100000055), Award ID: R01DC020707. Amanda Hampton Wray, National Institute on Deafness and Other Communication Disorders (https://dx.doi.org/10.13039/100000055), Award ID: R21DC017227. Amanda Hampton Wray, National Institute on Deafness and Other Communication Disorders (https://dx.doi.org/10.13039/100000055), Award ID: R01DC019904. Shahriar SheikhBahaei, National Institute of Neurological Disorders and Stroke (https://dx.doi.org/10.13039/100000065), Award ID: ZIA NS009420. Nan Bernstein Ratner, National Stuttering Association, Award ID: CASE grant. Nan Bernstein Ratner, National Science Foundation (https://dx.doi.org/10.13039/100000001), Award ID: BCS1626300. Kate Watkins, Medical Research Council (https://dx.doi.org/10.13039/501100000265), Award ID: MR/K023772/1 and MR/N025539/1. Kate Watkins, NIHR Oxford Biomedical Research Centre (https://dx.doi.org/10.13039/501100013373), Award ID: NIHR203316. Kate Watkins, Wellcome Trust (https://dx.doi.org/10.13039/100010269), Award ID: 203139/Z/16/Z and 203139/A/16/Z. National Institute on Deafness and Other Communication Disorders (https://dx.doi.org/10.13039/100000055), Award ID: R01DC00559.
dc.identifier.citationChang, S.-E., Below, J. E., Chow, H. M., Guenther, F. H., Hampton Wray, A. M., Jackson, E. S., Max, L., Neef, N. E., SheikhBahaei, S., Shekim, L., Tichenor, S. E., Walsh, B., Watkins, K. E., Yaruss, J. S., & Bernstein Ratner, N. (2025). Stuttering: Our current knowledge, research opportunities, and ways to address critical gaps. Neurobiology of Language, 6, nol_a_00162. https://doi.org/10.1162 /nol_a_00162
dc.identifier.issn2641-4368
dc.identifier.urihttps://udspace.udel.edu/handle/19716/36077
dc.language.isoen_US
dc.publisherNeurobiology of Language
dc.rightsAttribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectgenetics
dc.subjectintervention
dc.subjectneurobiology
dc.subjectresearch priorities
dc.subjectspeech disorder
dc.subjecttreatment
dc.titleStuttering: Our Current Knowledge, Research Opportunities, and Ways to Address Critical Gaps
dc.typeArticle

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