Update on the efficacy of vaccination on host immunity to influenza virus infection

Abstract

Abstract Influenza, commonly known as the flu, is a contagious respiratory illness caused by influenza viruses, primarily affecting the epithelial cells of the respiratory tract. There are several strains of the virus, with influenza A and B being the most significant in terms of public health impact. The immune system’s response to influenza infection plays a crucial role in determining the severity of the illness and the effectiveness of vaccination strategies. The immune system's response to the influenza virus is both complex and vital for recovery and immunity. Vaccination plays a key role in mitigating the impact of influenza, although its effectiveness can vary based on multiple factors. Continuous monitoring of circulating strains and advancements in vaccine technology are essential in improving prevention strategies and protecting public health. Ongoing research into novel vaccine strategies is crucial for achieving better efficacy and addressing vaccine hesitancy, ultimately leading to reduced morbidity and mortality associated with influenza. Key words: Influenza, TLRs, CTL, PRR, NK