Natural Product Synthesis by Intramolecular Alkylidene Carbene C−H Insertion
Date
2022-03-15
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
European Journal of Organic Chemistry
Abstract
Direct functionalization of unactivated C−H bonds is of increasing importance in organic synthesis. Of the many methods that have been developed, intramolecular alkylidene C−H insertion, proceeding with retention of absolute configuration, is among the most versatile. This Review explores all examples of the use of intramolecular alkylidene C−H insertion in natural product synthesis.
Description
This is the peer reviewed version of the following article: Taber, Douglass F. “Natural Product Synthesis by Intramolecular Alkylidene Carbene C−H Insertion.” European Journal of Organic Chemistry 2022, no. 10 (March 15, 2022). https://doi.org/10.1002/ejoc.202200032, which has been published in final form at https://doi.org/10.1002/ejoc.202200032. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited. This article will be embargoed until 03/15/2023.
Keywords
C−H Activation, Cyclization, Natural products, Synthetic methods
Citation
Taber, Douglass F. “Natural Product Synthesis by Intramolecular Alkylidene Carbene C−H Insertion.” European Journal of Organic Chemistry 2022, no. 10 (March 15, 2022). https://doi.org/10.1002/ejoc.202200032.