Exploring the role of ergothioneine and mycorrhizal fungi in shaping the wheat soil microbiome

Abstract

The association between plants and soil microbes is critical for both soil and plant health. Introducing beneficial microbial inoculants, such as arbuscular mycorrhizal fungi (AMF), can enhance the uptake of nutrients and compounds in plants including ergothioneine (ERGO), a well-known antioxidant and anti-inflammatory compound that humans must obtain through diet. However, little is known about how ERGO and inoculated AMF influence ERGO uptake in plants or affect soil microbiome composition, including bacteria, archaea, and fungi. This study investigates the interaction between soil-applied ERGO and AMF inoculation in plant–microbe symbioses to assess (1) whether these treatments increase ERGO content in the staple crop wheat (Triticum aestivum), and (2) how they alter soil microbiome structure.

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This article was originally published in Environmental Microbiome. The version of record is available at: https://doi.org/10.1186/s40793-026-00913-8 Open Access This article is licensed under a Creative Commons Attribution-Non Commercial-No Derivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

Citation

Ravi, S.S.N., Pipinos, A., Insley, N. et al. Exploring the role of ergothioneine and mycorrhizal fungi in shaping the wheat soil microbiome. Environmental Microbiome (2026). https://doi.org/10.1186/s40793-026-00913-8

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