Chicken pituitary transcriptomic responses to acute heat stress
Date
2023-05-02
Journal Title
Journal ISSN
Volume Title
Publisher
Molecular Biology Reports
Abstract
Background
Poultry production is vulnerable to increasing temperatures in terms of animal welfare and in economic losses. With the predicted increase in global temperature and the number and severity of heat waves, it is important to understand how chickens raised for food respond to heat stress. This knowledge can be used to determine how to select chickens that are adapted to thermal challenge. As neuroendocrine organs, the hypothalamus and pituitary provide systemic regulation of the heat stress response.
Methods and Results
Here we report a transcriptome analysis of the pituitary response to acute heat stress. Chickens were stressed for 2 h at 35 °C (HS) and transcriptomes compared with birds maintained in thermoneutral temperatures (25 °C).
Conclusions
The observations were evaluated in the context of ontology terms and pathways to describe the pituitary response to heat stress. The pituitaries of heat stressed birds exhibited responses to hyperthermia through altered expression of genes coding for chaperones, cell cycle regulators, cholesterol synthesis, transcription factors, along with the secreted peptide hormones, prolactin, and proopiomelanocortin.
Description
This article was originally published in Molecular Biology Reports. The version of record is available at: https://doi.org/10.1007/s11033-023-08464-8.
© The Author(s) 2023.
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Keywords
pituitary, chicken, heat stress, transcriptome, stress response, metabolism
Citation
Pritchett, E.M., Van Goor, A., Schneider, B.K. et al. Chicken pituitary transcriptomic responses to acute heat stress. Mol Biol Rep 50, 5233–5246 (2023). https://doi.org/10.1007/s11033-023-08464-8