Collision Sports and Neurodegenerative Disease: Inclusion of Moderating Risk Factors

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Exercise and Sport Sciences Reviews

Abstract

Collision sport participation with repetitive head impacts has been associated with increased risk of neurodegenerative diseases, but also have lower mortality rates for many individual conditions. The role of modifiable risk factors in later life development of neurodegenerative diseases in athletes is a clear knowledge gap and a potential opportunity for interventions to improve health related quality of life.

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This is a pre-copyedited, author-produced version of an article accepted for publication in Exercise and Sport Sciences Reviews. The published version of record Buckley, Thomas A., Jaclyn B Caccese, and John J Jela. “Collision Sports and Neurodegenerative Disease: Inclusion of Moderating Risk Factors.” Exercise and Sport Sciences Reviews, 9900. https://doi.org/10.1249/JES.0000000000000362 is available online at: https://doi.org/10.1249/JES.0000000000000362. Copyright © 2025 by the American College of Sports Medicine. Unauthorized reproduction of this article is prohibited. Exercise and Sport Sciences Reviews articles in the Published Ahead-of-Print section have been peer-reviewed and accepted for publication. However, during copyediting, page composition, or proof review changes may be made that could affect the content. This article will be embargoed until 05/01/2026.

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Buckley, Thomas A., Jaclyn B Caccese, and John J Jela. “Collision Sports and Neurodegenerative Disease: Inclusion of Moderating Risk Factors.” Exercise and Sport Sciences Reviews, 9900. https://doi.org/10.1249/JES.0000000000000362

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