The Synthesis and Use of Iron Oxide Colloidal Particles as the Support Material in HPLC
Date
2015-05
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Publisher
University of Delaware
Abstract
High Performance Liquid Chromatography (HPLC) is a very important separation technique. This study attempted to create nonspherical iron oxide-based colloidal particles to be used as the cores in core-shell particles used as the support material for the stationary phase used in HPLC. The cores were coated with an impenetrable layer of silica to protect the cores from breaking down and to keep solutes away from iron. A porous layer was then added to the cores using a silica sol that were held together by a polymer. All of the colloids synthesized in this study were characterized using SEM and FIB-SEM. This study also included the creation of a Continuous Flow Steric Field-Flow Fractionator to be used to separate colloidal particles based on size, density, and shape.
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Research Subject Categories::TECHNOLOGY::Chemical engineering, Research Subject Categories::TECHNOLOGY::Chemical engineering::Chemical process and manufacturing engineering, Chemical Engineering