Department: University of Delaware. Department of Animal and Food Sciences.
Publisher: BioMed Central
Date Issued: 2004
Abstract: The resolution of radiation hybrid (RH) maps is intermediate between that of the
genetic and BAC (Bacterial Artificial Chromosome) contig maps. Moreover, once framework RH
maps of a genome have been constructed, a quick location of markers by simple PCR on the RH
panel is possible. The chicken ChickRH6 panel recently produced was used here to construct a high
resolution RH map of chicken GGA5. To confirm the validity of the map and to provide valuable
comparative mapping information, both markers from the genetic map and a high number of ESTs
(Expressed Sequence Tags) were used. Finally, this RH map was used for testing the accuracy of
the chicken genome assembly for chromosome 5.
Pitel, F., Abasht, B., Morisson, M., Crooijmans, R. P. M. A., Vignoles, F., Leroux, S., . . . Vignal, A. (2004). A high-resolution radiation hybrid map of chicken chromosome 5 and comparison with human chromosomes. BMC Genomics, 5 doi:10.1186/1471-2164-5-66