Extent and consistency of linkage disequilibrium and identification of DNA markers for production and egg quality traits in commercial layer chicken populations
Date
2009
Journal Title
Journal ISSN
Volume Title
Publisher
BioMed Central
Abstract
The genome sequence and a high-density SNP map are now available for the chicken and
can be used to identify genetic markers for use in marker-assisted selection (MAS). Effective MAS requires
high linkage disequilibrium (LD) between markers and quantitative trait loci (QTL), and sustained marker-
QTL LD over generations. This study used data from a 3,000 SNP panel to assess the level and consistency
of LD between single nucleotide polymorphisms (SNPs) over consecutive years in two egg-layer chicken
lines, and analyzed one line by two methods (SNP-wise association and genome-wise Bayesian analysis) to
identify markers associated with egg-quality and egg-production phenotypes.
Description
Final published version
Keywords
Citation
Abasht, B., Sandford, E., Arango, J., Settar, P., Fulton, J. E., O'Sullivan, N. P., . . . Lamont, S. J. (2009). Extent and consistency of linkage disequilibrium and identification of DNA markers for production and egg quality traits in commercial layer chicken populations. BMC Genomics, 10(SUPPL. 2) doi:10.1186/1471-2164-10-S2-S2