Liu, Chuang; Perilla, Juan R.; Ning, Jiying; Lu, Manman; Hou, Guangjin; Ramalho, Ruben; Himes, Benjamin A.; Zhao, Gongpu; Bedwell, Gregory J.; Byeon, In-Ja; Ahn, Jinwoo; Gronenborn, Angela M.; Prevelige, Peter E.; Rousso, Itay; Aiken, Christopher; Polenova, Tatyana; Schulten, Klaus; Zhang, Peijun
(Nature Publishing Group, 2016-03-04)
The host cell factor cyclophilin A (CypA) interacts directly with the HIV-1 capsid and
regulates viral infectivity. Although the crystal structure of CypA in complex with the
N-terminal domain of the HIV-1 capsid protein ...